I've been running my Nexus 6P in small display mode since Friday, and I am pretty happy with the results because I can see more on the screen. For example, the lock screen notifications are more useful simply because more text displays.

I've also learned about Custom Quick Settings, which allows you to create panels in the quick settings shade that appears when you sweep down with two fingers from the top of the screen. While you can use Custom Quick Settings with Android 6 Marshmallow, I think Android N improves upon it by allowing you to further edit the panel with whatever panels you want.

I've created two panels to launch apps, one to launch SmartThings/Hue and the other to launch RadarScope/ WeatherUnderground. You swipe down with two fingers and tap once to launch SmartThings, tap twice to launch Hue.